A 13-year-old girl developed immune thrombocytopenic purpura following vaccination with a quadrivalent human papillomavirus (HPV) vaccine. - GreenMedInfo Summary

Abstract Title:

Vaccinations and secondary immune thrombocytopenia with antiphospholipid antibodies by human papillomavirus vaccine.

Abstract Source:

Semin Hematol. 2016 Apr ;53 Suppl 1:S48-50. Epub 2016 Apr 7. PMID: 27312165

Abstract Author(s):

Mojca Bizjak, Or Bruck, Darja Kanduc, Sonja Praprotnik, Yehuda Shoenfeld

Article Affiliation:

Mojca Bizjak

Abstract:

A 13-year-old girl developed immune thrombocytopenic purpura (ITP) and concomitant positive antiphospholipid antibodies (aPL) following vaccination with a quadrivalent human papillomavirus (HPV) vaccine. During the course of a disease, she developed clinical manifestation with bleeding and she was treated with intravenous immunoglobulins. Consequently, the number of her platelets remained critically low and she was put on corticosteroids and rituximab. Since then, her platelet count remain within the normal range, but her aPL are still present.

Article Published Date : Mar 31, 2016
Study Type : Human: Case Report
Additional Links
Diseases : Autoimmune Diseases : CK(11441) : AC(2477), Thrombocytopenia : CK(287) : AC(47)
Additional Keywords : Molecular Mimicry : CK(109) : AC(32)
Anti Therapeutic Actions : Vaccination: HPV (Gardasil) : CK(578) : AC(97)

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Key Research Topics

Disease

Autoimmune Diseases
Thrombocytopenia

Anti-Therapeutic Action

Vaccination: HPV (Gardasil)

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