Activity of Allyl Isothiocyanate and Its Synergy with Fluconazole againstBiofilms.
J Microbiol Biotechnol. 2017 Apr 28 ;27(4):685-693. PMID: 28138121
Jayant Shankar Raut
Candidiasis involving the biofilms ofis a threat to immunocompromised patients.biofilms are intrinsically resistant to the antifungal drugs and hence novel treatment strategies are desired. The study intended to evaluate the anti-activity of allyl isothiocyanate (AITC) alone and with fluconazole (FLC), particularly against the biofilms. Results revealed the concentration-dependent activity of AITC against the planktonic growth and virulence factors of. Significant (<0.05) inhibition of the biofilms was evident at