Abstract Title:

Recent development of acupuncture on Parkinson's disease.

Abstract Source:

Neurol Res. 2010 Feb;32 Suppl 1:5-9. PMID: 20034437

Abstract Author(s):

Tong H Joh, Hi-Joon Park, Seung-Nam Kim, Hyejung Lee


OBJECTIVES: Parkinson's disease is a complex disease with multiple etiological factors involved in disease pathogenesis, and the molecular and cellular pathways for neurodegeneration are still elusive. METHODS: We reviewed all the relevant laboratory findings regarding acupuncture mechanism on Parkinson's disease. RESULTS: Acupuncture treatments in animal experiments have generated valuable mechanistic insights of Parkinson's disease and shown that acupuncture therapy is in fact a neuroprotective therapy which increases various neuroprotective agents such as brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor and cyclophilin A. In addition, acupuncture therapy decreases cell death processes and attenuates oxidative stress to substantia nigra dopaminergic neurons. DISCUSSION: These results suggest that early application of acupuncture therapy for Parkinson's disease patients may be helpful for the best efficacy of acupuncture treatment.

Study Type : Commentary
Additional Links
Therapeutic Actions : Acupuncture : CK(2697) : AC(307)

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