Acute cholestatic hepatitis associated with pravastatin has been reported. - GreenMedInfo Summary

Abstract Title:

Acute cholestatic hepatitis associated with pravastatin.

Abstract Source:

Am J Gastroenterol. 1999 May ;94(5):1388-90. PMID: 10235223

Abstract Author(s):

M Hartleb, G Rymarczyk, K Januszewski

Article Affiliation:

Department of Gastroenterology, Silesian Medical School, Katowice, Poland.

Abstract:

A 57-yr-old man presented with clinical and laboratory signs of acute cholestatic hepatitis. Symptoms had appeared 7 wk after he was started on pravastatin 20 mg/day for hypercholesterolemia. A full evaluation including ultrasound, computed tomography, endoscopic cholangiography, and liver biopsy confirmed the diagnosis of intrahepatic nonobstructive jaundice. The liver function abnormalities normalized 7 wk after cessation of therapy. Pravastatin should be considered as a potential cause of cholestatic hepatitis with favorable clinical outcome after drug withdrawal.

Article Published Date : May 01, 1999
Study Type : Human: Case Report
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(1157) : AC(504), Cholestasis : CK(125) : AC(36), GGT : CK(63) : AC(9), Hepatitis: Cholestatic : CK(28) : AC(10), Statin-Induced Pathologies : CK(1638) : AC(327)
Pharmacological Actions : Anticholesteremic Agents : CK(2126) : AC(382)
Problem Substances : Pravastatin : CK(251) : AC(42), Statin Drugs : CK(4369) : AC(517)
Adverse Pharmacological Actions : Hepatotoxic : CK(335) : AC(96)

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Key Research Topics

Pharmacological Actions

Anticholesteremic Agents

Disease

Statin-Induced Pathologies
Chemically-Induced Liver Damage
Cholestasis
GGT
Hepatitis: Cholestatic

Toxic Ingredients

Statin Drugs
Pravastatin

Adverse Pharmacological Actions

Hepatotoxic
Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.