Article Publish Status: FREE
Abstract Title:

Acute disseminated encephalomyelitis associated with oral polio vaccine.

Abstract Source:

Intern Med. 2006 ;45(20):1143-6. Epub 2006 Nov 15. PMID: 17106158

Abstract Author(s):

Kensaku Shibazaki, Tatsufumi Murakami, Ryutaro Kushida, Katsumi Kurokawa, Kihei Terada, Yoshihide Sunada

Article Affiliation:

Kensaku Shibazaki


A 27-year-old woman presented with acute paresis after taking an oral polio vaccine (OPV). Deep tendon reflexes were preserved, needle electromyography showed no neurogenic changes, and there were no lesions on spine magnetic resonance imaging (MRI), suggesting that motor neurons of the spinal cord were not affected. Brain MRI showed abnormal lesions in the tegmentum of the upper pons, left cerebral peduncles, truncus of the corpus callosum, and right parietal lobe. Cerebrospinal fluid revealed mild pleocytosis. The most probable diagnosis was acute disseminated encephalomyelitis associated with OPV.

Study Type : Human: Case Report
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