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Article Publish Status: FREE
Abstract Title:

AduoLa Fuzhenglin down-regulates microwave-induced expression ofβ1-adrenergic receptor and muscarinic type 2 acetylcholine receptor in myocardial cells of rats.

Abstract Source:

Biomed Environ Sci. 2014 Mar ;27(3):204-7. PMID: 24709101

Abstract Author(s):

Jing Zhang, Rui Yun Peng, Ya Bing Gao, Shui Ming Wang, Lei Lei Yang, Li Zhao, Ji Dong, Bin Wei Yao, Gong Min Chang, Lu Xiong

Article Affiliation:

Jing Zhang

Abstract:

This paper is aimed to study the effect of ADL on expression ofβ1-AR and M2-AchR in myocardial cells of rats exposed to microwave radiation. Immunohistochemistry, Western blot and image analysis were used to detect the expression of β1-AR and M2-AchR in myocardial cells at 7 and 14 d after microwave exposure. The results show that the expression level was higher in microwave exposure group and 0.75 g/(kg•d) ADL group than in sham operation group and significantly lower in 1.5 and 3.0 g/(kg•d) ADL groups than in microwave group. So we have a conclusion that the expression of β1-AR and M2-AchR is down-regulated in myocardial cells of rats exposed tomicrowave radiation. ADL can protect rats against microwave-induced heart tissue injury.

Study Type : In Vitro Study

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Sayer Ji
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