Agrimony induces programmed cell death in human promyelocytic leukemia cells. - GreenMedInfo Summary

Abstract Title:

[Experimental study on decoctum Agrimonia pilosa Ledeb-induced apoptosis in HL-60 cells in vitro].

Abstract Source:

Antibiotiki. 1978 Jul;23(7):633-6. PMID: 12575284

Abstract Author(s):

K Gao, L Zhou, J Chen, F Li, L Zhang

Abstract:

In this study, MTT assay, cell morphology and flow cytometry were used to explore Agrimonia pilosa Ledeb on HL-60 cells in vitro. The data suggested that Agrimonia pilosa Ledeb had the effects of growth inhibition in HL-60 cells. After treated with decoctum Agrimonia pilosa Ledeb, cells underwent apoptosis with typical morphological feature. DNA histograms by flow cytometric analysis displayed distinct apoptotic peak.

Article Published Date : Jul 01, 1978
Study Type : In Vitro Study
Additional Links
Substances : Agrimony : CK(18) : AC(25)
Diseases : Promyelocytic leukemia : CK(137) : AC(130)
Pharmacological Actions : Apoptotic : CK(6986) : AC(6931)

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Key Research Topics

Pharmacological Actions

Apoptotic

Disease

Promyelocytic leukemia

Substance

Agrimony

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