Air pollution exposures and blood pressure variation in type-2 diabetes mellitus patients. - GreenMedInfo Summary
Air pollution exposures and blood pressure variation in type-2 diabetes mellitus patients: A retrospective cohort study in China.
Ecotoxicol Environ Saf. 2019 Apr 30 ;171:206-210. Epub 2018 Dec 31. PMID: 30605850
Air pollution exposure has been associated with hypertension, but limited studies have examined the associations in diabetic patients. We aimed to examine the associations of exposure to air pollution with blood pressure in diabetic patients. We identified patients who were previously diagnosed as type-2 diabetes mellitus from hospital records from January 2013 to May 2017. We used generalized linear models to estimate adverse effects of air pollution on systolic/diastolic blood pressure in diabetic patients. A total of 40,125 patients were enrolled in this study. An IQR increase in PM, PM, NO, SO, and Oexposure was associated with an increased risk of higher systolic blood pressure level (β = 0.628 for PM,β = 0.758 for PM,β = 0.766 for NO,β = 0.516 for SO,β = 0.482 for O, all P value < 0.05). Significant associations were observed for some air pollutants and SBP among patients with fasting blood glucose (FBG) ≥ 7.0 mmol/L, normal weight, and younger age. Little evidence was available for the associations between particulate matter (PM) or Oexposure and diastolic blood pressure in present study. In our study, diabetic patients were at increased risk of higher blood pressure when exposed to higher residential PM, NOand SO. Individuals with lower BMI, younger age, and FBG ≥ 7.0 mmol/L were more susceptible to the adverse effects of ambient air pollution.