Abstract Title:

American ginseng tea protects cellular DNA within 2 h from consumption: results of a pilot study in healthy human volunteers.

Abstract Source:

Int J Food Sci Nutr. 2015 ;66(7):815-8. Epub 2015 Sep 22. PMID: 26393910

Abstract Author(s):

Yim Tong Szeto, Yuk Shan Pauline Sin, Sok Cheon Pak, Wouter Kalle

Article Affiliation:

Yim Tong Szeto


The acute genoprotective effect of Panax quinquefolius (American ginseng) has been investigated. The experiment was carried out to explore the DNA protective effect after a single dose of American ginseng tea bag infusion. Fourteen subjects (6 males and 8 females) were recruited in this study. Seven of them (3 males and 4 females) were asked to drink a cup of freshly prepared American ginseng infusions. Water was taken by the remaining subjects as the control group. Blood samples of both groups were taken before and 2 h post-ingestion. The blood samples were challenged with ultraviolet B irradiation followed by using comet assay. Completed slides were stained with Giemsa stain and DNA damage was assessed. Results showed a significant decrease in comet score after American ginseng supplementation and no changein the control group. The current study demonstrated a cup of American ginseng infusion could protect cellular DNA from oxidative stress at least within 2 h.

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