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Article Publish Status: FREE
Abstract Title:

Therapeutic Effects of Anthocyanins for Vision and Eye Health.

Abstract Source:

Molecules. 2019 Sep 11 ;24(18). Epub 2019 Sep 11. PMID: 31514422

Abstract Author(s):

Yuri Nomi, Keiko Iwasaki-Kurashige, Hitoshi Matsumoto

Article Affiliation:

Yuri Nomi

Abstract:

Anthocyanin (AC) is widely used as supplement of eye health in Europe and in East Asia. In this review, I describe AC effects to clarify the mechanism is important in order to understand the effects of AC on vision health. The bioavailability of AC is quite low but, reported as intact form and many kinds of metabolite. And AC passes through the blood-aqueous fluid barrier and blood-retinal barrier. In vitro study, AC had a relaxing effect on ciliary muscle which is important to treat both myopia and glaucoma. And AC stimulate the regeneration of rhodopsin in frog rod outer segment. Furthermore, AC could inhibit the axial length and ocular length elongation in a negative lens-induced chick myopia model. In addition, we summarized clinical studies of AC intake improved dark adaptation and transient myopic shift and the improvement on retinal blood circulation in normal tension glaucoma patients.

Study Type : Review
Additional Links
Pharmacological Actions : Regenerative : CK(52) : AC(28)

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