Anti-hepatitic activity of ginsenoside Ro. - GreenMedInfo Summary

n/a

Abstract Title:

Anti-hepatitic activity of ginsenoside Ro.

Abstract Source:

Planta Med. 1991 Dec ;57(6):523-6. PMID: 1818342

Abstract Author(s):

H Matsuda, K Samukawa, M Kubo

Article Affiliation:

H Matsuda

Abstract:

Ginsenoside Ro, an oleanane-type saponin has been screened for activity in experimental models of acute and chronic hepatitis. Ginsenoside Ro (50 and 200 mg/kg, p.o.) inhibited the increase of serum glutamic oxaloacetic transaminase (s-GOT) and serum glutamic pyruvic transaminase (s-GPT) levels in D-galactosamine (GalN)- and carbon tetrachloride (CCl4)-induced acute hepatitic rats. Ginsenoside Ro inhibited the increase of connective tissue in the liver of CCl4-induced chronic hepatitic rats. Ginsenoside Ro showed a stronger inhibitory effect on the GalN-induced acute hepatitic model than those of the aglycone of ginsenoside Ro, oleanolic acid, or glycyrrhizic acid and its aglycone, glycyrrhetinic acid.

Article Published Date : Nov 30, 1991

Study Type : Animal Study

Additional Links

Substances : Ginsenosides : CK(1550) : AC(1330)

Diseases : Chemically-Induced Liver Damage : CK(1565) : AC(1010)

Pharmacological Actions : Hepatoprotective : CK(5098) : AC(3517)

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Printer-friendly version

Anti-hepatitic activity of ginsenoside Ro. - GreenMedInfo Summary

Print Options

Key Research Topics

Substance

Disease

Pharmacological Actions

Subscribe to our informative Newsletter & receive Cancer Fighting Foods Ebook

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.