n/a
Article Publish Status: FREE
Abstract Title:

Anti-Inflammatory Effect of Musa acuminata Stem.

Abstract Source:

Eur J Dent. 2020 Mar ;14(2):294-298. Epub 2020 May 12. PMID: 32396971

Abstract Author(s):

Maharani Laillyza Apriasari, Selviana Rizky Pramitha, Dewi Puspitasari, Diah Savitri Ernawati

Article Affiliation:

Maharani Laillyza Apriasari

Abstract:

OBJECTIVE:  This study was designed to assess the anti-inflammatory effect ofthrough the expression of tumor necrosis factor-α (TNF-α) and nuclear factor kappa β (NF-κB) after 3 days of application of(MASE) gel on oral mucosal wound.

MATERIALS AND METHODS:  An experimental study with post-test only control group design was conducted. Twenty male(Wistar) were injured on their left buccal mucosa and treated three times a day with MASE gel of varying concentrations: 0% (as control), MASE 25%, MASE 37.5%, and MASE 50%. On day 3, a biopsy was performed on each mucosal wound for later immunohistochemical analysis for the expressions of TNF-α and NF-κB.

RESULTS:  The highest expression of TNF-α was observed in the control group (13.20 ± 1.79), while the lowest was in the treatment group using 50% MASE (6.40 ± 1.14). Meanwhile the comparison between treatment groups did not highlight any significant difference (>0.05). The highest expression of NF-κB was observed in the control group (13.20 ± 1.30), whereas the lowest was in the treatment group using MASE 50% (6.40 ± 1.14). NF-κB was significantly lower in the treatment group using MASE 50% when compared with other treatment groups (<0.05).

CONCLUSION:  Application of MASE on mucosal wound reduces the expression of TNF-α and NF-κB at all concentrations. The anti-inflammatory effect of MASE 50% was the strongest one.

Print Options


Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.