Abstract Title:

Anti-proliferative effects of a blueberry extract on a panel of tumor cell lines of different origin.

Abstract Source:

Exp Oncol. 2020 06 ;42(2):101-108. PMID: 32602283

Abstract Author(s):

H Lamdan, R S Garcia-Lazaro, N Lorenzo, L G Caligiuri, D F Alonso, H G Farina

Article Affiliation:

H Lamdan


BACKGROUND: Blueberries are among the fruits with the highest antioxidant activity and have been recognized by their health promoting properties.

AIM: In vitro study of the anti-proliferative effects of a blueberry extract on a panel of cancer cells from different origin.

MATERIALS AND METHODS: A blueberry extract was produced using ethanol as extracting solvent. The anti-proliferative activity of the extract was evaluated against seven tumor cell lines. The properties of blueberry extract to decrease cell adhesion and migration were also investigated.

RESULTS: Blueberry extract showed a dose-dependent inhibitory effect on cell proliferation for all cell lines. Non-cytotoxic concentrations of the extract decreased cell adhesion in five of seven cell lines studied and inhibited the migration of MDA-MB-231 and PC-3 tumor cells.

CONCLUSION: This work provides additional evidence regarding the ability of blueberry extract to inhibit the growth and decrease cell adhesion and migration of different cancer cell lines in vitro.

Study Type : In Vitro Study

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.