Antibacterial and Antibiofilm Activities ofSp. Essential Oil and Cinnamaldehyde: Antimicrobial Activities.
ScientificWorldJournal. 2018 ;2018:7405736. Epub 2018 Jun 6. PMID: 29977171
Diego F Firmino
To assess the activities of essential oils derived from the trunk bark of(EOCz) and(EOCc) as well as cinnamaldehyde on bacterial biofilms of clinical interest. Antimicrobial activity was assessed by the broth microdilution method to determine minimum inhibitory concentrations (MICs). Antibiofilm activity was assessed by quantifying the biomass and determining the number of viable cells. The chemical composition of the essential oils was determined. The results showed that the major component of EOCz and EOCc was cinnamaldehyde. For the assayed substances, biofilm biomasses were reduced by up to 99.9%, and,, andbiofilms were sensitive to all of the concentrations and substances analysed. In cell viability tests, 2 mg/ml of cinnamaldehyde reduced the number of viable cells by 5.74 Log CFU/ml. EOCz, EOCc, and cinnamaldehyde exhibited antimicrobial and antibiofilm activities. This work describes substances with potential use against infections caused by bacterial biofilms.