Antifungal effect of tea extracts on Candida albicans. - GreenMedInfo Summary
Antifungal effect of tea extracts on Candida albicans.
Dent Mater J. 2020 Apr 3. Epub 2020 Apr 3. PMID: 32249233
Determining whether tea extracts are effective in removing Candida albicans (C. albicans) from dentures is of interest. This study aimed to investigate the antifungal effect of tea extracts on C. albicans. One green tea (Anji white tea, AGW) and 2 oolong teas (Tie Guan Yin, TGY; Da Hong Pao, DHP) of different concentrations were tested. C. albicans suspensions were inoculated on the plates and the numbers of colony-forming units (CFU) in the culture medium were used to screen for the optimum tea extracts. Polymethyl methacrylate (PMMA) specimens that contained C. albicans biofilms were then treated with the tea extracts and the numbers of CFU were counted. The antifungal activities of the tea extracts were not significantly correlated with their catechin concentrations. Although AGW at 10.0 mg/mL and DHP at 2.5 mg/mL significantly inhibited C. albicans in the culture medium, the extracts failed to exert inhibitory effects against C. albicans biofilms on the PMMA surfaces.