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Article Publish Status: FREE
Abstract Title:

Antimicrobial and Anti-Quorum Sensing Activities of Phlorotannins From Seaweed ().

Abstract Source:

Front Cell Infect Microbiol. 2020 ;10:586750. Epub 2020 Oct 30. PMID: 33194827

Abstract Author(s):

Jiali Tang, Wenqian Wang, Weihua Chu

Article Affiliation:

Jiali Tang

Abstract:

Multidrug-resistant bacteria (MDR) are becoming a global health problem, and scientists are continuously investigating new strategies to fight against MDR. Seaweeds are an important source of biological compounds and can serve as natural sources for bacterial infection control. This study evaluated the antimicrobial and anti-quorum sensing (QS) activities of phlorotannins from. The phlorotannins exhibited antimicrobial activity against selected bacterial pathogens and inhibited QS activity of the reporter strain12472 by inhibiting purple pigment production. Phlorotannins can decrease the bacterial motility, reduce the production of extracellular protease, hemolysin, and pyocyanin and inhibit biofilm formation of.studies showed that phlorotannins can reduceinflicted mortality in. This study shows that phlorotannins fromhave certain antimicrobial and anti-quorum sensing activities and have the potential to control bacterial infection for pharmaceutical usage.

Study Type : In Vitro Study

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