n/a
Article Publish Status: FREE
Abstract Title:

The Antimicrobial and Antiviral Activity of Polyphenols from Almond (L.) Skin.

Abstract Source:

Nutrients. 2019 Oct 3 ;11(10). Epub 2019 Oct 3. PMID: 31623329

Abstract Author(s):

Maria Musarra-Pizzo, Giovanna Ginestra, Antonella Smeriglio, Rosamaria Pennisi, Maria Teresa Sciortino, Giuseppina Mandalari

Article Affiliation:

Maria Musarra-Pizzo

Abstract:

Due to their antimicrobial and antiviral activity potential in vitro, polyphenols are gaining a lot of attention from the pharmaceutical and healthcare industries. A novel antiviral and antimicrobial approach could be based on the use of polyphenols obtained from natural sources. Here, we tested the antibacterial and antiviral effect of a mix of polyphenols present in natural almond skin (NS MIX). The antimicrobial potential was evaluated against the standard American Type Culture Collection (ATCC) and clinical strains of, including methicillin-resistant (MRSA) strains, by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Herpes simplex virus type I was used for the antiviral assessment of NS MIX by plaque assay. Furthermore, we evaluated the expression of viral cascade antigens. NS MIX exhibited antimicrobial (MIC values of 0.31-1.25 mg/ml) and antiviral activity (decrease in the viral titer **<0.01, and viral DNA accumulation *<0.05) againstand HSV-1, respectively. Amongst the isolated compounds, the aglycones epicatechin and catechin showed the greatest activity againstATCC 6538P (MIC values of 0.078-0.15 and 0.15 mg/ml, respectively), but were not active against all the other strains. These results could be used to develop novel products for topical use.

Print Options


Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.