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Article Publish Status: FREE
Abstract Title:

Antimicrobial, antioxidant and anticancer activities of,andextracts.

Abstract Source:

Saudi Pharm J. 2018 Jan ;26(1):44-52. Epub 2017 Nov 10. PMID: 29379332

Abstract Author(s):

Nouf M Al-Enazi, Amani S Awaad, Mohamed E Zain, Saleh I Alqasoumi

Article Affiliation:

Nouf M Al-Enazi

Abstract:

The antimicrobial, antioxidant, and anticancer activities of ethanolic extract ofwere determined. The highest antibacterial activity; 23.40 ± 0.58 mm (00.98 µg/ml) and 22.60 ± 2.10 mm (03.90 µg/ml) were obtained againstbyand, respectively. However,showed excellent antibacterial activity against(21.7 ± 1.5 mm; 1.95 µg/ml),(21.7 ± 0.58 mm; 1.95 µg/ml),(20.7 ± 1.2 mm; 1.95 µg/ml) and(20.1 ± 1.2 mm; 3.9 µg/ml). Moreover, the highest antifungal activity; 24.7 ± 2.0 mm (0.98 µg/ml), 23.7 ± 1.5 mm (0.98 µg/ml), 23.6 ± 1.5 mm (0.98 µg/ml) was obtained byagainst,and, respectively. The algal extracts showed DPPH radical scavenging activity in a concentration-dependent manner with maximum scavenging activity (77.6%, IC = 5.59 µg/ml and 77.07%, IC = 14.3 µg/ml) was provided byand, respectively. Theantitumor activity revealed that the ICvalues ofwere 58.9, 115.0, 54.5, 59.0, 101.0, 101.0, and 97.6 µg/ml;were 55.2, 96.8, 104.0, 78.7, 117.0, 217.0, 169.0 µg/ml; andwere 115.0, 221.0, 225.0, 200.0, 338.0, 242.0, and 189.0 µg/ml; respectively against A-549 (Lung carcinoma), Caco-2 (Intestinal carcinoma), HCT-116 (Colon carcinoma), Hela (Cervical carcinoma), HEp-2 (Larynx carcinoma), HepG-2 (Hepatocellular carcinoma), and MCF-7 (Breast carcinoma) cell lines.

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