Article Publish Status: FREE
Abstract Title:

Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc.

Abstract Source:

Molecules. 2016 Apr 7 ;21(4):457. Epub 2016 Apr 7. PMID: 27070557

Abstract Author(s):

Shi-Fei Li, Jia-Yin Ding, Ya-Ting Li, Xiao-Jiang Hao, Shun-Lin Li

Article Affiliation:

Shi-Fei Li


Continued interest in the metabolites of Wedelia trilobata (L.) Hitchc, a notoriously invasive weed in South China, led to the isolation of twenty-six ent-kaurane diterpenoids, including seven new ones 1-7. Their structures and relative configuration were elucidated on the basis of extensive spectroscopic analysis, including 1D- and 2D-NMR experiments. The antimicrobial activities of all isolated diterpenoids were evaluated against a panel of bacteria and fungi.

Study Type : In Vitro Study

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