Abstract Title:

Antioxidant role of morusin and mulberrofuran B in ethanol extract ofroots.

Abstract Source:

Nat Prod Res. 2020 Aug 25:1-4. Epub 2020 Aug 25. PMID: 32840147

Abstract Author(s):

Bruna de Almeida Martins, Denise Sande, Maykelis Díaz Solares, Jacqueline Aparecida Takahashi

Article Affiliation:

Bruna de Almeida Martins


The white mulberry,, is distributed worldwide and known for its antioxidant properties. Ethanol extract of six varieties ofroots were studied (IZ 13/6, IZ 40, IZ 56/4, IZ 64, Indonesia and Tigreada). From variety IZ 40, two secondary metabolites were isolated and unambiguously identified by 2 D NMR experiments as morusin and mulberrofuran B. These were quantified in the varieties by liquid chromatography, recording 5.27-16.74% for the first, and 0.54-3.55% for the latter. Mulberrofuran B presented higher activity than morusin by phosphomolybdenum (1531.33 ± 20.28 mmol ascorbicacid/g) and ferrocyanide (14.39%) methods, ABTS (95.74 ± 4.21 µM) and DPPH (843.87 ± 10.65 µM) radical sequestration capacity, while morusin showed significant statistical correlation with antioxidant activity for somevarieties. These results suggested that morusin influences antioxidant activity ofin synergism with other compounds and can be a good chemical marker in this species.

Study Type : In Vitro Study

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