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Abstract Title:

Antiproliferative and antiviral activity of methanolic extracts from Sardinian Maltese Mushroom (L.).

Abstract Source:

Nat Prod Res. 2019 Oct 17:1-5. Epub 2019 Oct 17. PMID: 31621410

Abstract Author(s):

Sarah Vascellari, Paolo Zucca, Daniela Perra, Alessandra Serra, Alessandra Piras, Antonio Rescigno

Article Affiliation:

Sarah Vascellari

Abstract:

is a non-photosynthetic plant that grows in Mediterranean countries and that is amply used in the traditional medicine. The aim of this study was to extend previous studies on the chemical and biological properties ofevaluating the potential antiviral and antiproliferative activity of the methanolic extract. The MTT assay was used for thecytotoxic studies against human cancer-derived cell lines, while both MTT and plaque reduction (PRT) methods were used to evaluate the potential inhibitory effect of the extract against a panel of mammal viruses. The results obtained showed no selective activity against any DNA and RNA virus but revealed an interesting antiproliferative activity against human leukaemia-derived cell lines.

Study Type : In Vitro Study

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