Arnica montana gel is safe, well-tolerated and effective in the treatment of mild to moderate osteoarthritis of the knee - GreenMedInfo Summary
Arnica montana gel in osteoarthritis of the knee: an open, multicenter clinical trial.
Adv Ther. 2002 Sep-Oct;19(5):209-18. PMID: 12539881
Department of Rheumatology, Valens Clinic for Rheumatism, Valens, Switzerland.
This open multicenter trial investigated the safety and efficacy of an Arnica montana fresh plant gel, applied twice daily, in 26 men and 53 women with mild to moderate osteoarthritis (OA) of the knee. After 3 and 6 weeks, significant decreases in median total scores on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were evident in the intention-to-treat and per-protocol populations (both P<.0001). Scores on the pain, stiffness, and function subscales also showed significant reductions at these timepoints. The overall local adverse-event rate of 7.6% included only one allergic reaction. Sixty-nine patients (87%) rated the tolerability of the gel as "good" or "fairly good," and 76% would use it again. Topical application of Arnica montana gel for 6 weeks was a safe, well-tolerated, and effective treatment of mild to moderate OA of the knee.