Assessment of bisphenol A levels in preschool children-Results of a human biomonitoring study in Ankara, Turkey
J Clin Res Pediatr Endocrinol. 2019 Sep 2. Epub 2019 Sep 2. PMID: 31475509
Objective: There is general concern regarding environmental chemical exposures and the impact it may have on human health, which is particularly important for vulnerable populations such as infants and children in critical periods of development. Bisphenol A (BPA) is an endocrine disrupting chemical used worldwide over the last 30 years in many consumer products that play an important role in our daily life. The aim of this study was to evaluate the exposure of Turkish preschool children to BPA.
Methods: This study conducted a preliminary investigation of BPA in urine collected from 3-6 year old children (mean age: 4.50±1.26) living in Ankara. For this purpose, after spot urine samples were taken from preschool children (n=125; Males n= 70, Females n=55), free BPA, β-D-glucuronide (BPA-GLU) and total BPA were determined using high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS).
Results: Total BPA was detected in 76.8% of children from Ankara city, with concentrations ranging from
Conclusion: This study is an important contribution to the limited information about childhood exposure to BPA.