Abstract Title:

Ayahuasca, an ancient substance with traditional and contemporary use in neuropsychiatry and neuroscience.

Abstract Source:

Epilepsy Behav. 2019 Jun 7. Epub 2019 Jun 7. PMID: 31182391

Abstract Author(s):

Rafael Guimarães Dos Santos, Jaime Eduardo Cecilio Hallak

Article Affiliation:

Rafael Guimarães Dos Santos


Ayahuasca is a botanical hallucinogenic preparation traditionally used for ritual and therapeutic purposes by native populations of the Northwestern Amazon. In the last decades, ayahuasca use has spread to Europe, the United States, Asia, and Africa, and interest in the possible therapeutic uses of ayahuasca for treating anxiety and mood disorder and substance-use disorders has increased both among the general public and the scientific community. Indeed, preclinical, observational, and preliminary clinical studies have corroborated some of these findings. In the present article, we present an overview of these studies and highlight the current uses of ayahuasca in neuroscience, such as a tool in the investigation of the neural basis of introspection and other complex cognitive processes.

Study Type : Review

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