Antibacterial and Cytotoxic Effects of(Moringa) and(Neem) Methanolic Extracts against Strains of.
Int J Dent. 2018 ;2018:1071676. Epub 2018 Sep 25. PMID: 30356384
Objective: To evaluate antibacterial and cytotoxic effect of 2 methanolic extracts ofandagainst strains of(ATCC 29212).
Methods: The methanolic extracts ofandwere prepared. The antibacterial effect of the extracts againstwas evaluated using the agar diffusion technique. The minimum inhibitory concentration (MIC) was determined using the microdilution method and the cytotoxicity using the cellular line MDCK.
Results: The methanolic extract with the most antibacterial effect during the first 24 and 48 hours againstwas, evidencing a growth inhibition zone of 35.5 ± 1.05 and 44.83 ± 0.98, respectively. The MIC for both extracts was 75 g/ml. The bactericidal effect of theextract was found at a concentration of 25 g/ml and a concentration of 75 g/ml forextract.
Conclusions: In conclusion, we demonstrated that the methanolic extract ofandboth have an antibacterial effect againststrains during the first 24 and 48 hours. None of the extracts exhibited toxicity against the cell lines under low concentrations.