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Abstract Title:

Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities.

Abstract Source:

J Nat Prod. 2007 May;70(5):795-801. Epub 2007 May 5. PMID: 17480099

Abstract Author(s):

Surat Boonphong, Pakawan Puangsombat, Apiwat Baramee, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop

Article Affiliation:

Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.

Abstract:

Eleven new secondary metabolites (1-11), together with two known flavanones (12 and 13) and five known bibenzyls (14-18), were isolated from the root extract of Bauhinia purpurea. New compounds include eight dihydrodibenzoxepins (1-8), a dihydrobenzofuran (9), a novel spirochromane-2,1'-hexenedione (10), and a new bibenzyl (11). Antimycobacterial, antimalarial, antifungal, cytotoxic, and anti-inflammatory activities of the isolated compounds are reported, and biosynthetic pathways of these compounds are also discussed.

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