Article Publish Status: FREE
Abstract Title:

The Benefits of Omega-3 Fats for Stabilizing and Remodeling Atherosclerosis.

Abstract Source:

Mo Med. 2020 Jan-Feb;117(1):65-69. PMID: 32158053

Abstract Author(s):

James J DiNicolantonio, James H O'Keefe

Article Affiliation:

James J DiNicolantonio


The majority of acute coronary syndromes are caused by the rupture of plaques rendered vulnerable by oxidized lipids, inflammation, and a thin fibrous cap with reduced collagen and smooth muscle cell content.2 Thus, stabilizing and reversing vulnerable atherosclerotic plaques can help to prevent cardiovascular events. In this regard, long-chain omega-3 fatty acids have a plethora of data for stabilizing vulnerable atherosclerotic plaques as well as reversing atherosclerosis. This review paper will summarize the observational data as well as animal and human studies supporting such a role and further discuss the current controversies around omega-3 supplementation.

Study Type : Review

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Sayer Ji
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