Article Publish Status: FREE
Abstract Title:

Antimicrobial Activity ofHoney and Characterization of Its Bioactive Compounds in Comparison With Important Commercial Honeys.

Abstract Source:

Front Microbiol. 2019 ;10:263. Epub 2019 Feb 25. PMID: 30858831

Abstract Author(s):

Sushil Anand, Margaret Deighton, George Livanos, Paul D Morrison, Edwin C K Pang, Nitin Mantri

Article Affiliation:

Sushil Anand


There is an urgent need for new effective antimicrobial agents since acquired resistance of bacteria to currently available agents is increasing. The antimicrobial activity of Mono-floralhoney produced from Australian grownwas compared with the activity of commercially available honeys derived fromspecies and with Jarrah honey for activity against clinical and non-clinical strains of(methicillin-susceptible and methicillin-resistant strains),, and. The minimum inhibitory concentration (MIC) forhoney was in the range of 6-25% (w/v) for all species examined. The MICs forhoneys were generally similar to those ofhoney, but MICs were higher for Super manuka and Jarrah honeys and lower for Tea tree honey. Staphylococci were more susceptible to all honeys thanand. Pretreatment of honey with catalase increased the bacterial growth at MIC of Tea tree honey (35%), Super Manuka (15%), Jarrah honeys (12%), andhoney (10%), indicating variable contributions of hydrogen peroxide to antimicrobial activity. Manuka and Jelly bush honeys retained their antimicrobial activity in the presence of catalase, indicating the presence of other antimicrobial compounds in the honey. An LC-MS/MS method was developed and used to identify possible antimicrobial phenolic compounds inhoney and flowers, and five commercial honeys. The chemical markers characteristic ofhoney and honeys oforigin were phenyllactic acid and methyl syringate. Overall, the bioactive compounds with antimicrobial and antioxidant activity inhoney suggested a possible use for topical application and in wound care.

Print Options

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.