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Article Publish Status: FREE
Abstract Title:

Biological Activities of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments.

Abstract Source:

Oxid Med Cell Longev. 2016 ;2016:4973239. Epub 2016 Jun 20. PMID: 27413420

Abstract Author(s):

Shuang Ling, Jin-Wen Xu

Article Affiliation:

Shuang Ling

Abstract:

2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside (THSG) is active component of the Chinese medicinal plant Polygonum multiflorum Thunb. (THSG). Pharmacological studies have demonstrated that THSG exhibits numerous biological functions in treating atherosclerosis, lipid metabolism, vascular and cardiac remodeling, vascular fibrosis,cardiac-cerebral ischemia, learning and memory disorders, neuroinflammation, Alzheimer and Parkinson diseases, diabetic complications, hair growth problems, and numerous other conditions. This review focuses on the biological effects of THSG in antiaging and antiaging-related disease treatments anddiscusses its molecular mechanisms.

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