Abstract Title:

Exposure to a commercial glyphosate formulation (Roundup®) alters normal gill and liver histology and affects male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes).

Abstract Source:

Arch Environ Contam Toxicol. 2012 Jan ;62(1):107-17. Epub 2011 Jun 4. PMID: 21643816

Abstract Author(s):

Andrea Cecilia Hued, Sabrina Oberhofer, María de losÁngeles Bistoni

Article Affiliation:

Laboratory of Animal Diversity II, Faculty of Exact, Physical, and Natural Sciences, National University of Córdoba, Av. Vélez Sársfield 299, CP 5000, Córdoba, Argentina. [email protected]

Abstract:

Roundup is the most popular commercial glyphosate formulation applied in the cultivation of genetically modified glyphosate-resistant crops. The aim of this study was to evaluate the histological lesions of the neotropical native fish, Jenynsia multidentata, in response to acute and subchronic exposure to Roundup and to determine if subchronic exposure to the herbicide causes changes in male sexual activity of individuals exposed to a sublethal concentration (0.5 mg/l) for 7 and 28 days. The estimated 96-h LC50 was 19.02 mg/l for both male and female fish. Gill and liver histological lesions were evaluated through histopathological indices allowing quantification of the histological damages in fish exposed to different concentrations of the herbicide. Roundup induced different histological alterations in a concentration-dependent manner. In subchronic-exposure tests, Roundup also altered normal histology of the studied organs and caused a significant decrease in the number of copulations and mating success in male fish exposed to the herbicide. It is expected that in natural environments contaminated with Roundup, both general health condition and reproductive success of J. multidenatata could be seriously affected.

Study Type : Animal Study

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