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Abstract Title:

Exposure to bisphenol A and diabetes risk in Mexican women.

Abstract Source:

Environ Sci Pollut Res Int. 2019 Jul 9. Epub 2019 Jul 9. PMID: 31286379

Abstract Author(s):

Luke Murphy, Ángel Mérida-Ortega, Mariano E Cebrián, Lucia Hernández-Garciadiego, Humberto Gómez-Ruiz, Brenda Gamboa-Loira, Lizbeth López-Carrillo

Article Affiliation:

Luke Murphy

Abstract:

Bisphenol A (BPA) is an endocrine-disrupting chemical widely used in the production of polycarbonate plastics and epoxy resins, which has been previously linked to diabetes among non-Hispanic populations. As part of a case control study for breast cancer, only controls with BPA information were included in this report. The final sample size comprises 70 self-reported diabetics and 334 non-diabetics. Urinary free bisphenol A (BPA-F) (μg/L) was determined by solid-phase extraction and HPLC/FLD analysis. Logistic regression models were used to evaluate the association between BPA-F and self-reported diabetes. After adjusting by age, urinary BPA-F (4.06-224.53 μg/g creatinine) was associated with diabetes exposure (OR = 1.85;95% CI 1.04, 3.28) compared with women in the reference category (0.67-4.05 μg/g creatinine). BPA may be an environmental cofactor of diabetes. More studies are needed to confirm this result, especially in Hispanic populations.

Study Type : Human Study

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