Calophyllum seed oil contain coumarins with anti-HIV activity. - GreenMedInfo Summary
Abstract Title:
Anti-HIV coumarins from Calophyllum seed oil.
Abstract Source:
Bioorg Med Chem Lett. 1998 Dec 15;8(24):3475-8. PMID: 9934455
Article Affiliation:
Université de Sherbrooke, Département de Chimie, Qc., Canada.
Abstract:
The seeds of Calophyllum cerasiferum Vesque (Family-Clusiaceae), and Calophyllum inophyllum Linn. (Family-Clusiaceae) contain several known coumarins, among which were the potent HIV reverse transcriptase inhibitors costatolide and inophyllum P. Calophyllum cerasiferum contained (-)-calanolide B as its major coumarin constituent in significant amount and thus constitute a renewable source of this compound.
Article Published Date : Dec 15, 1998
Study Type : In Vitro Study
Additional Links
Substances : Calophyllum brasiliense : CK(3) : AC(4)
Diseases : HIV Infections : CK(1055) : AC(393)
Pharmacological Actions : Anti-HIV Agents : CK(133) : AC(95), Reverse Transcriptase Inhibitors : CK(47) : AC(31)
