Abstract Title:

Camel milk lactoferrin reduces the proliferation of colorectal cancer cells and exerts antioxidant and DNA damage inhibitory activities.

Abstract Source:

Food Chem. 2013 Nov 1 ;141(1):148-52. Epub 2013 Mar 21. PMID: 23768340

Abstract Author(s):

Hosam M Habib, Wissam H Ibrahim, Regine Schneider-Stock, Hassan M Hassan

Article Affiliation:

Hosam M Habib

Abstract:

Lactoferrin (Lf), the main iron-binding protein of milk, has biological activities. We have evaluated the potential of camel milk lactoferrin for its ability to inhibit the proliferation of the colon cancer cell line, HCT-116, in vitro, DNA damage and its antioxidant activities for the first time. The antioxidant capacity of Lf was evaluated by different assays, including ferric-reducing/antioxidant power assay (FRAP), free radical-scavenging activity (DPPH), nitric oxide (NO) radical-scavenging assay, total antioxidant activity and DNA damage, compared with vitamin C and rutin.

Study Type : In Vitro Study

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