Abstract Title:

Does vitamin D deficiency trigger carpal tunnel syndrome?

Abstract Source:

J Back Musculoskelet Rehabil. 2016 Mar 31. Epub 2016 Mar 31. PMID: 27062466

Abstract Author(s):

Nermin Tanik, Özlem Balbaloğlu, Mehmet Ucar, Umıt Sarp, Tugay Atalay, Asuman Çelikbilek, Ayşe Yeşim Göçmen, Levent Ertugrul Inan

Article Affiliation:

Nermin Tanik


OBJECTIVE: Vitamin D deficiencies are associated with a variety of chronic diseases. The goal of the present study was to investigate the relationship between vitamin D levels and carpal tunnel syndrome (CTS).

METHODS: This study included 90 patients with mild to moderate CTS and assessed their routine serum 25-hydroxyvitamin D levels. Additionally, the pain level of each subject was evaluated using the Visual Analogue Scale and the Douleur Neuropathique 4 Questionnaire (DN4).

RESULTS: The severity levels of CTS were at a 75% mild level in the vitamin D deficiency group and a 47.1% mild level in the vitamin D normal group, with a significant difference between groups (p = 0.008). Correlation analyses revealed positive correlations between body mass index and DN4 scores (r = 0.499, p = 0.025) and between vitamin D levels and CTS severity (r = 0.364, p = 0.004) in the vitamin D deficiency group.

CONCLUSIONS: The present findings demonstrated that CTS may be triggered by vitamin D deficiency, and that the severity of CTS was correlated with vitamin D levels in the deficiency group. Additionally, there was a correlation between weight gain and neuropathic pain intensity in CTS patients with vitamin D deficiency. The present findings indicate that vitamin D levels should be assessed in CTS patients.

Study Type : Human Study

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Sayer Ji
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