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Article Publish Status: FREE
Abstract Title:

Oseltamivir (Tamiflu)-induced Bilateral Ciliochoroidal Effusion and Angle Closure Glaucoma: What Type of Idiosyncratic Reaction?

Abstract Source:

J Ophthalmic Vis Res. 2017 Oct-Dec;12(4):434-436. PMID: 29090056

Abstract Author(s):

Shahin Yazdani, Hamed Esfandiari, Sare Safi, Alireza Fatemi

Article Affiliation:

Shahin Yazdani

Abstract:

PURPOSE: To report a case of bilateral acute angle closure glaucoma after one dose of oseltamivir 75 mg.

CASE REPORT: A 37-year-old man with a history of influenza developed high intraocular pressure and uniformly shallow anterior chamber in both eyes, 5 hours after the first dose of oseltamivir 75 mg. The condition was managed successfully with topical cycloplegic and systemic/topical antiglaucoma medications.

CONCLUSION: Since a presumed idiosyncratic reaction developed right after the first dose of the medication, it challenges the common concept of adaptive immune system involvement in this type of reaction in medication-related ciliochoroidal effusion.

Study Type : Human: Case Report
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