Article Publish Status: FREE
Abstract Title:

Acute disseminated encephalomyelitis following inactivated influenza vaccination in the Brazilian Amazon: a case report.

Abstract Source:

Rev Soc Bras Med Trop. 2015 Jul-Aug;48(4):498-500. PMID: 26312942

Abstract Author(s):

Solange Dourado de Andrade, Maria Graciede Filha Santarém Andrade, Pablo José Santos, Maria de Lourdes Galvão, Mariana Martins de Barros, Rajendranath Ramasawmy, Izabella Picinin Safe, Wuelton Marcelo Monteiro, Meritxell Sabidó, Maria das Graças Costa Alecrim

Article Affiliation:

Solange Dourado de Andrade


Here, we describe a case of acute disseminated encephalomyelitis (ADEM) that occurred during a plausible risk interval following inactivated influenza vaccination in a previously healthy 27-year-old man from Manaus, Brazil. He was treated with intravenous methylprednisolone and immunoglobulin. One-month follow-up revealed resolution of the brain lesions, but not of the spinal cord lesions. No recurrence or progression of the main neurological symptoms was observed. After two years of monitoring, the patient continues to experience weak lower limbs and urinary retention. Thus, we recommend that ADEM should be considered in a patient presenting with neurological symptoms after influenza vaccination.

Study Type : Human: Case Report
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