A case report of spontaneous regression of locally advanced nonsmall cell lung cancer. - GreenMedInfo Summary
Spontaneous regression of locally advanced nonsmall cell lung cancer: A case report.
Medicine (Baltimore). 2018 Aug ;97(31):e11291. PMID: 30075496
Kiat Huat Ooi
RATIONALE: Spontaneous regression of non-small cell lung cancer is exceptionally rare.
PATIENT CONCERNS: Treatment-related toxicity.
DIAGNOSES: We report a case of a patient diagnosed with locally advanced non-small cell lung cancer.
INTERVENTIONS: The patient declined potentially curative treatment, and did not receive any anti-cancer treatment.
OUTCOMES: He has survived more than two years since his initial diagnosis, maintaining his good performance status. Serial imaging with computed tomography scans showed tumour regression and near-complete resolution of his disease.
LESSONS: Spontaneous regression of non-small cell lung cancer, by virtue of its scarcity, has not been well-studied and is poorly understood. Further studies are required, in order to clarify the mechanisms by which spontaneous regression occurs, and possibly identify new targets for cancer treatment.