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Abstract Title:

An unusual mimicker of a sepsis outbreak: ergot intoxication.

Abstract Source:

Eur J Pediatr. 2011 May ;170(5):633-7. Epub 2010 Oct 23. PMID: 20972685

Abstract Author(s):

Ahmet Yagmur Bas, Nihal Demirel, Ahmet Soysal, Kahraman Arslan, Ugur Dilmen

Article Affiliation:

Ahmet Yagmur Bas

Abstract:

Methylergonovine (MEV) is a semi-synthetic ergot alkaloid used in the prevention and control of postpartum hemorrhage. This report describes 12 newborns born on the same day in a local country hospital in Turkey and developed sepsis-like symptoms and encephalopathy within the first 6 h of life due to accidental administration of MEV instead of vitamin K in the delivery room. The major features of MEV poisoning were lethargy (41.7%), seizure (75.0%), feeding intolerance (66.6%), hypoventilation (58.3%), irritability (25%), and peripheral circulatory abnormalities (58.3%). As a conclusion, clinical findings of ergot toxicity in newborns cannot be distinguished from infectious disease or neonatal encephalopathy.

Study Type : Human: Case Report

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