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Abstract Title:

A generalized reaction to thimerosal from an influenza vaccine.

Abstract Source:

Ann Allergy Asthma Immunol. 2005 Jan ;94(1):90-4. PMID: 15702823

Abstract Author(s):

Mary Lee-Wong, David Resnick, Kaman Chong

Article Affiliation:

Mary Lee-Wong

Abstract:

BACKGROUND: Thimerosal is a preservative commonly used in ophthalmic solutions, otic drops, and vaccines because of its bactericidal property.

OBJECTIVE: To report a case of a generalized reaction to thimerosal in a patient who received an influenza vaccine.

METHODS: We describe a patient who developed a generalized maculopapular eruption after receiving a thimerosal-containing influenza vaccine. Patch testing was performed to determine if there was an allergy to thimerosal.

RESULTS: Patch testing confirmed a T-cell-mediated sensitivity to thimerosal.

CONCLUSIONS: Physicians need to be aware that thimerosal is found in many products, including vaccinations. Clinicians should also be aware that allergic reactions occur with exposure to thimerosal even in vaccines. To our knowledge, this is the first case report in the literature of a generalized reaction to thimerosalfrom an influenza vaccine.

Study Type : Human: Case Report
Additional Links
Additional Keywords : Vaccine Research : CK(20) : AC(1)
Anti Therapeutic Actions : Vaccination: All : CK(6351) : AC(662)
Problem Substances : Thimerosal : CK(618) : AC(151)

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Sayer Ji
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