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Article Publish Status: FREE
Abstract Title:

Measles Outbreak with Unique Virus Genotyping, Ontario, Canada, 2015.

Abstract Source:

Emerg Infect Dis. 2017 07 ;23(7):1063-1069. PMID: 28628461

Abstract Author(s):

Shari Thomas, Joanne Hiebert, Jonathan B Gubbay, Effie Gournis, Jennifer Sharron, Alberto Severini, Manisa Jiaravuthisan, Amanda Shane, Valerie Jaeger, Natasha S Crowcroft, Jill Fediurek, Beate Sander, Tony Mazzulli, Helene Schulz, Shelley L Deeks

Article Affiliation:

Shari Thomas

Abstract:

The province of Ontario continues to experience measles virus transmissions despite the elimination of measles in Canada. We describe an unusual outbreak of measles in Ontario, Canada, in early 2015 that involved cases with a unique strain of virus and no known association among primary case-patients. A total of 18 cases of measles were reported from 4 public health units during the outbreak period (January 25-March 23, 2015); none of these cases occurred in persons who had recently traveled. Despite enhancements to case-patient interview methods and epidemiologic analyses, a source patient was not identified. However, the molecular epidemiologic analysis, which included extended sequencing, strongly suggested that all cases derived from a single importation of measles virus genotype D4. The use of timely genotype sequencing, rigorous epidemiologic investigation, and a better understanding of the gaps in surveillance are needed to maintain Ontario's measles elimination status.

Study Type : Human Study

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Sayer Ji
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