Abstract Title:

A pilot randomized double-blind placebo-controlled trial on topical chamomile (Matricaria chamomilla L.) oil for severe carpal tunnel syndrome.

Abstract Source:

Complement Ther Clin Pract. 2015 Nov ;21(4):223-8. Epub 2015 Aug 12. PMID: 26573447

Abstract Author(s):

Mohammad Hashem Hashempur, Zeinab Nasiri Lari, Parissa Sadat Ghoreishi, Babak Daneshfard, Mohammad Sadegh Ghasemi, Kaynoosh Homayouni, Arman Zargaran

Article Affiliation:

Mohammad Hashem Hashempur


OBJECTIVE: To assess the effectiveness of standardized topical Chamomile (Matricaria chamomilla L.) oil in patients with severe carpal tunnel syndrome, as a complementary treatment.

METHOD: A pilot randomized double-blind placebo-controlled trial was conducted. Twenty six patients with documented severe carpal tunnel syndrome were treated in two parallel groups with a night splint plus topical chamomile oil or placebo. They were instructed to use their prescribed oil for 4 weeks, twice daily. Symptomatic and functional status of the patients and their electrodiagnostic parameters were evaluated when enrolled and after the trial period, as our outcome measures.

RESULTS: A significant improvement of symptomatic and functional status of patients in the chamomile oil group was observed (p = 0.019 and 0.016, respectively) compared with those in the placebo group. However, electrodiagnostic parameters showed no significant changes between the two groups.

CONCLUSION: Chamomile oil improved symptomatic and functional status of patients with severe carpal tunnel syndrome.

Study Type : Human Study

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Sayer Ji
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