Chemical constituents of Brazilian Propolis from the state of Bahia and their growth inhibitory activities against cancer cells.
Biosci Biotechnol Biochem. 2018 Mar ;82(3):417-421. Epub 2018 Jan 26. PMID: 29370717
A novel 2-phenoxychromone (1) and five known flavones (2-6) were isolated from northeastern Brazilian propolis in the state of Bahia. The chemical structures of these six compounds were determined by spectroscopic investigations and single-crystal X-ray analysis. The isolated compounds showed growth-inhibitory activities, in varying degrees, against human tumor cell lines. This is the first report on the discovery of a novel 2-phenoxychromone from propolis.