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Article Publish Status: FREE
Abstract Title:

Chemoprevention by Triticum Aestivum of mouse skin carcinogenesis induced by DMBA and croton oil - association with oxidative status.

Abstract Source:

Asian Pac J Cancer Prev. 2011 ;12(1):143-8. PMID: 21517247

Abstract Author(s):

Priyanka Arya, Madhu Kumar

Article Affiliation:

Priyanka Arya

Abstract:

Chemopreventive action of wheat grass (Triticum astivum) leaf extract in Swiss albino mice was evaluated. Oral administration of wheat grass leaf extract at a dose level of 20 ml/kg body weight per day at pre, peri, and post-initional phases and in combination group, caused significant variation in tumour incidence and tumour yield as compared to the control group. Moreover, the average latent period was significantly increased from 9.87± 0.12 to 13.4 ± 0.23 weeks in the combination group, together with significant elevation of reduced glutathione (GSH), superoxide dismutase (SOD) catalase (CAT) and reduction in lipid peroxidation (LPO) was observed as compared to the control group.

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