Abstract Title:

The effect of cinnamon extract on insulin resistance parameters in polycystic ovary syndrome: a pilot study.

Abstract Source:

Nutrition. 2001 Apr;17(4):315-21. PMID: 17296187

Abstract Author(s):

Jeff G Wang, Richard A Anderson, George M Graham, Micheline C Chu, Mark V Sauer, Michael M Guarnaccia, Rogerio A Lobo

Abstract:

Cinnamon extract has been shown to reduce insulin resistance in in vitro and in vivo studies by increasing phosphatidylinositol 3-kinase activity in the insulin signaling pathway and thus potentiating insulin action. Fifteen women with polycystic ovary syndrome (PCOS) were randomized to daily oral cinnamon and placebo for 8 weeks. Comparisons of post-treatment to baseline insulin sensitivity indices using fasting and 2-hour oral glucose tolerance tests showed significant reductions in insulin resistance in the cinnamon group but not in the placebo group. A larger trial is needed to confirm the findings of this pilot study and to evaluate the effect of cinnamon extract on menstrual cyclicity.

Study Type : Human Study

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Sayer Ji
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