Article Publish Status: FREE
Abstract Title:

Effects of cinnamon supplementation on antioxidant status and serum lipids in women with polycystic ovary syndrome.

Abstract Source:

J Tradit Complement Med. 2018 Jan ;8(1):128-133. Epub 2017 May 19. PMID: 29322000

Abstract Author(s):

Azam Borzoei, Maryam Rafraf, Shirin Niromanesh, Laya Farzadi, Fateme Narimani, Farideh Doostan

Article Affiliation:

Azam Borzoei


Background: The objectives of study were to investigate the effects of cinnamon supplementation on antioxidant status and serum lipids in women with polycystic ovary syndrome (PCOS).

Methods: This double-blind randomized controlled clinical trial was conducted on 84 overweight or obese PCOS patients; aged 20-38 years. Subjects in cinnamon (n = 42) and placebo (n = 42) groups were given 3 cinnamon capsules (each one contained 500 mg cinnamon) or placebo daily for 8 weeks. Fasting blood samples, anthropometric measurements and dietary intake data were gathered at the beginning and at the end of the study. Independent t test, pairedt test and analysis of covariance were used to analyze of data.

Results: Cinnamon significantly increased serum total antioxidant capacity (P = 0.005). Malondialdehyde was significantly decreased compared with placebo (P = 0.014). Cinnamon supplementation significantly improved serum level of total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol (all P < 0.05). No significant effect was detected on serum triglyceride level.

Conclusions: Cinnamon supplementation improved antioxidant status and serum lipid profile in women with PCOS and may be applicable for reducing PCOS risk factors.

Study Type : Human Study

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