Citrus fruit peel and seed extract demonstrates anti Epstein-Barr virus activity. - GreenMedInfo Summary
Inhibitory effect of Epstein-Barr virus activation by Citrus fruits, a cancer chemopreventor.
Cancer Lett. 1999 May 24;139(2):227-36. PMID: 10395183
Full Citation: "To search useful compounds in Citrus fruit for cancer chemoprevention, we carried out a primary screening of extracts of fruit peels and seeds from 78 species of the genus Citrus and those from two Fortunella and one Poncirus species, which were closely related to the genus Citrus. These Citrus extracts inhibited the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol 13-acetate (TPA) as a useful screening method for anti-tumor promoters. Our results indicated that Citrus containing substances may be inhibit susceptibility factors involved in the events leading to the development of cancer."