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Article Publish Status: FREE
Abstract Title:

Why we need a clinical trial for vitamin K.

Abstract Source:

BMJ. 1994 Apr 2 ;308(6933):908-10. PMID: 8173376

Abstract Author(s):

J M Slattery

Article Affiliation:

J M Slattery

Abstract:

Vitamin K is given to many babies born in the United Kingdom, but we still do not know if it has substantial hazards. Because the population exposed to vitamin K is very large even quite small hazards would involve many adverse events. It is therefore important to be able to put reasonably close bounds on the potential damage that vitamin K prophylaxis could cause. Past research has not allowed us to do this but a large randomised controlled clinical trial of vitamin K against no vitamin K, enrolling only infants at low risk of haemorrhagic disease, would do so. There is no question that vitamin K is a useful treatment in babies at highest risk of haemorrhagic disease: the question is whether the trend towards use of vitamin K in lower risk babies should be encouraged.

Study Type : Review
Additional Links
Anti Therapeutic Actions : Vitamin K injections : CK(26) : AC(3)

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