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Abstract Title:

Composition and potential anticancer activities of essential oils obtained from myrrh and frankincense.

Abstract Source:

Oncol Lett. 2013 Oct ;6(4):1140-1146. Epub 2013 Aug 8. PMID: 24137478

Abstract Author(s):

Yingli Chen, Chunlan Zhou, Zhendan Ge, Yufa Liu, Yuming Liu, Weiyi Feng, Sen Li, Guoyou Chen, Taiming Wei

Article Affiliation:

Yingli Chen

Abstract:

The present study aimed to investigate the composition and potential anticancer activities of essential oils obtained from two species, myrrh and frankincense, by hydrodistillation. Using gas chromatography-mass spectrometry (GC-MS), 76 and 99 components were identified in the myrrh and frankincense essential oils, respectively, with the most abundant components, 2-Cyclohexen-1-one, 4-ethynyl-4-hydroxy-3,5,5-trimethyl- and-Octylacetate, accounting for 12.01 and 34.66%, respectively. The effects of the two essential oils, independently and as a mixture, on five tumor cell lines, MCF-7, HS-1, HepG2, HeLa and A549, were investigated using the MTT assay. The results indicated that the MCF-7 and HS-1 cell lines showed increased sensitivity to the myrrh and frankincense essential oils compared with the remaining cell lines. In addition, the anticancer effects of myrrh were markedly increased compared with those of frankincense, however, no significant synergistic effects were identified. The flow cytometry results indicated that apoptosis may be a major contributor to the biological efficacy of MCF-7 cells.

Study Type : In Vitro Study

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