Abstract Title:

Cryogun cryotherapy for oral leukoplakia.

Abstract Source:

Head Neck. 2012 Sep ;34(9):1306-11. Epub 2011 Nov 15. PMID: 22084001

Abstract Author(s):

Hung-Pin Lin, Hsin-Ming Chen, Shih-Jung Cheng, Chuan-Hang Yu, Chun-Pin Chiang

Article Affiliation:

Hung-Pin Lin


BACKGROUND: Our previous study showed that cotton-swab cryotherapy is an alternative treatment modality for oral leukoplakia.

METHODS: This study used liquid nitrogen spray with a cryogun (cryogun cryotherapy) to treat 60 oral leukoplakia lesions.

RESULTS: Complete regression was achieved in all 60 oral leukoplakia lesions after cryogun cryotherapy. We found that 60 oral leukoplakia lesions treated with cryogen cryotherapy needed significantly fewer mean treatments (3.1± 1.3) to achieve complete regression than 60 previously reported oral leukoplakia lesions treated with cotton-swab cryotherapy (mean, 6.3 ± 3.8 treatments). Oral leukoplakia lesions on oral mucosal sites other than the tongue,<2 cm(2) , with epithelial dysplasia, or with a surface keratin thickness<55μm required significantly fewer cryogun cryotherapy treatments to achieve complete regression.

CONCLUSIONS: For treatment of oral leukoplakia, the cryogun cryotherapy needed fewer mean treatments to achieve complete regression of the lesions than the cotton-swab cryotherapy.

Study Type : Human Study
Additional Links
Therapeutic Actions : Cryotherapy : CK(10) : AC(1)

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