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Abstract Title:

Daily oral intake ofβ-cryptoxanthin ameliorates neuropathic pain.

Abstract Source:

Biosci Biotechnol Biochem. 2017 May ;81(5):1014-1017. Epub 2017 Jan 23. PMID: 28110620

Abstract Author(s):

Gyujin Park, Tetsuhiro Horie, Takashi Iezaki, Maika Okamoto, Kazuya Fukasawa, Takashi Kanayama, Kakeru Ozaki, Yuki Onishi, Minoru Sugiura, Eiichi Hinoi

Article Affiliation:

Gyujin Park

Abstract:

β-cryptoxanthin, a xanthophyll carotenoid, exerts preventive effects on various lifestyle-related diseases. Here, we found that daily oral administration of β-cryptoxanthin significantly ameliorated the development of tactile allodynia following spinal nerve injury but was ineffective in mechanical allodynia in an inflammatory pain model in mice. Our results suggest that β-cryptoxanthin supplementation would be beneficial for the prophylaxis of neuropathic pain.

Study Type : Animal Study

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